DEEP TISSUE VOLUMETRIC OPTOACOUSTIC TRACKING OF INDIVIDUAL CIRCULATING TUMOR CELLS IN AN INTRACARDIALLY PERFUSED MOUSE MODEL

Deep tissue volumetric optoacoustic tracking of individual circulating tumor cells in an intracardially perfused mouse model

Widespread metastasis is the major cause of death from melanoma and other types of cancer.At present, the dynamic aspects of the metastatic cascade remain enigmatic.The feasibility to track circulating melanoma cells deep within living intact organisms can greatly impact our knowledge on tumor metastasis, but existing imaging approaches lack the se

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Early life stress induced sex-specific changes in behavior is paralleled by altered locus coeruleus physiology in BALB/cJ mice

Adverse childhood experiences have been associated with many neurodevelopmental and affective disorders including attention deficit hyperactivity disorder and generalized anxiety disorder, with more exposures increasing negative risk.Sex and genetic background are biological variables involved in adverse psychiatric outcomes due to early life traum

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